Seroquel (Quetiapine)
Seroquel is an atypical antipsychotic used to treat bipolar disorder, schizophrenia, and major depression as an add-on. At lower doses it is also commonly prescribed for sleep and anxiety, though these are off-label uses.
Most clients pay around $20 per session with insurance.
Seroquel works by affecting dopamine and serotonin receptors in the brain. Its active ingredient, quetiapine, is a versatile medication used across a spectrum of psychiatric conditions and is often added to an antidepressant when a first medication alone is not providing full relief.
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Komal Nathani
MD, Psychiatrist
Dr. Nathani works with clients on medication management that considers both clinical need and personal values, including conversations around fasting, stigma, and family concerns about psychiatric care.
Adam Butera
MD Psychiatrist
Dr. Butera provides thoughtful psychiatric evaluations and medication management, taking each client's full life, including their faith and values, into account when building a treatment plan.
Real questions. Honest answers.
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Seroquel (quetiapine) is FDA-approved for schizophrenia, bipolar disorder (manic and depressive episodes), and as an add-on for major depression. At low doses it is frequently used off-label for insomnia and anxiety.
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At low doses (25–100mg), Seroquel has a sedating effect. While not FDA-approved for this purpose, psychiatrists sometimes prescribe it short-term for insomnia when other medications have not worked.
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Sedation, weight gain, dry mouth, constipation, and dizziness are common. Metabolic changes (blood sugar, cholesterol) should be monitored with long-term use.
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It can — particularly at higher doses. Your psychiatrist will monitor your weight and metabolic health and may recommend dietary adjustments.
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Seroquel is not considered addictive in the way benzodiazepines are, but it should not be stopped abruptly — withdrawal symptoms such as insomnia and nausea can occur.
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Yes, many people take it long-term safely. Regular monitoring of metabolic markers (glucose, cholesterol, weight) is important.
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For sleep and acute mania, effects are usually felt quickly. For depression and anxiety, improvement typically takes 2–4 weeks.
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Book a free consult at Outspace. Our psychiatrists will assess your full history and determine whether Seroquel is appropriate for your needs.