Abilify (Aripiprazole)
Abilify is an atypical antipsychotic that partially activates dopamine receptors rather than simply blocking them. It is used for bipolar disorder, schizophrenia, and as an add-on for depression, and is generally better tolerated than older antipsychotics.
Most clients pay around $20 per session with insurance.
Abilify is often chosen when weight gain or sedation from other antipsychotics is a concern. Its unique mechanism — partial agonism at dopamine receptors — gives it a different side effect profile compared to most antipsychotics, making it well-suited to long-term use.
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Komal Nathani
MD, Psychiatrist
Dr. Nathani works with clients on medication management that considers both clinical need and personal values, including conversations around fasting, stigma, and family concerns about psychiatric care.
Adam Butera
MD Psychiatrist
Dr. Butera provides thoughtful psychiatric evaluations and medication management, taking each client's full life, including their faith and values, into account when building a treatment plan.
Real questions. Honest answers.
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Abilify (aripiprazole) is FDA-approved for schizophrenia, bipolar I disorder, as an adjunct for major depression, irritability in autism, and Tourette's disorder.
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Most antipsychotics block dopamine receptors. Abilify partially activates them — a subtler action that tends to cause less sedation and less weight gain than many alternatives.
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It can cause some weight gain, but generally less than many other antipsychotics. Metabolic monitoring is still recommended.
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Restlessness (akathisia), headache, nausea, insomnia, and constipation. Akathisia — an uncomfortable urge to move — can be distressing but is manageable with dose adjustment.
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Yes — unlike many antipsychotics, Abilify can feel stimulating rather than sedating. For some people this is welcome; for others it can cause insomnia or restlessness.
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Yes, with regular monitoring. Your psychiatrist will check for metabolic changes and movement-related side effects at routine appointments
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For acute symptoms of mania or psychosis, some improvement is typically seen within 1–2 weeks. Full stabilisation may take 4–6 weeks.
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Book a free consult. Our psychiatrists will assess your history and determine whether Abilify is the right addition to your care plan.